Nickel-Catalyzed Removal of Alkene Protecting Group of Phenols, Alcohols via Chain Walking Process

Selective trimethylsilylation of alcohols and phenols with hexamethyldisilazane catalyzed by LaCoO3 perovskite

Trimethylsilylation of alcohols and phenols were carried out under solvent-free conditions with hexamethyldisilazane (HMDS) using LaCoO3 perovskite. LaCoO3 as an efficient catalyst accelerated this reaction under milder condition. The advantages of this method are evident regarding, easy separation, low cost and low catalyst loading, lack of pollution, easy work-up, and selective protection of ...

Synthesis of chromans via Pd-catalyzed alkene carboetherification reactions.

A new method for the construction of 2-substituted and 2,2-disubstituted chromans via Pd-catalyzed carboetherification reactions between aryl/alkenyl halides and 2-(but-3-en-1-yl)phenols is described. These reactions effect formation of a C-O bond and a C-C bond to afford the chroman products in good yield, and also provide stereoselective access to tricyclic chroman derivatives.

Nickel (0) Catalyzed Kumada Chain Transfer Polycondensation

Origins of regioselectivity and alkene-directing effects in nickel-catalyzed reductive couplings of alkynes and aldehydes.

The origins of reactivity and regioselectivity in nickel-catalyzed reductive coupling reactions of alkynes and aldehydes were investigated with density functional calculations. The regioselectivities of reactions of simple alkynes are controlled by steric effects, while conjugated enynes and diynes are predicted to have increased reactivity and very high regioselectivities, placing alkenyl or a...

Selective conversion of alcohols and phenols to tetrahydropyranyl ethers catalyzed with N-chlorosaccharin under mild and solvent-free conditions

An efficient method is described for the mild and rapid tetrahydropyranylation of alcohols and phenols using a catalytic amount of N-chlorosaccharin (1 mol %) and 3, 4-dihydro-2H-pyran under solvent-free condition at room temperature. Benzylic alcohols and phenols containing electron withdrawing or donating groups in various positions of phenyl ring, cinamyl alcohol, primary, ...